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Report any new or worsening symptoms to your doctorsuch asmood or behavior changesanxietydepressionpanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallyor have thoughts about suicide or hurting yourself.

Extended release tabletsAplenzinInitial dose174 mg orally once a day in the morningequivalent to 150 mg bupropion HClMaintenance doseAfter at least 4 daysthe dose may be increased to 348 mg once a dayequivalent to 300 mg bupropion HClIf there is not adequate improvement after several weeksthe dose may be increased to a maximum of 522 mg once a day in the morningequivalent to 450 mg bupropion HCl

Adverse events for which frequencies are provided below occurred in clinical trials with the sustained-release formulation of bupropionThe frequencies represent the proportion of patients who experienced a treatment-emergent adverse event on at least one occasion in placebo-controlled studies for depressionn987or smoking cessationn1,013or patients who experienced an adverse event requiring discontinuation of treatment in an open-label surveillance study with the sustained-release formulation of bupropionn3,100All treatment-emergent adverse events are included except those listed in Tables 2 through 5those events listed in other safety-related sectionsthose adverse events subsumed under COSTART terms that are either overly general or excessively specific so as to be uninformativethose events not reasonably associated with the use of the drugand those events that were not serious and occurred in fewer than 2 patientsEvents of major clinical importance are described in the WARNINGS and PRECAUTIONS sections of the labeling.

Home drugs a-z list Budeprion XL(Bupropion Hydrochloride Extended-Release Tabletsside effects drug center.

Postmarketing reportsMuscle rigiditymuscle weaknessmusculoskeletal chest painrhabdomyolysisRef]

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