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Take with or without foodTake Zetiaezetimibeat the same time of dayTo gain the most benefitdo not miss dosesKeep taking Zetiaezetimibeas you have been told by your doctor or other health care providereven if you feel well.

Ezetimibewhich is water insolubleis absorbed and extensively conjugated to an active phenolic glucuronideezetimibeglucuronideafter oral intakeAfter a single dosemean ezetimibe peak plasma concentrationsC maxof 3.4 to 5.5 ngmL were obtained within 4 to 12 hoursT maxThe extent of ezetimibe absorption is not affected by taking it with high-fat or nonfat mealsHoweverthe C max value of ezetimibe is increased by 38when taken with a high-fat mealOverallezetimibe may be taken with or without food3

Take this medication regularly to get the most benefit from itTo help you remembertake it at the same time each day.

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due to the unknown effects of the increased exposure to ezetimibe in patients with moderate to severe hepatic impairment, zetia is not recommended in these patients.

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