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Exposure of an unborn child to this medication could cause birth defectsso you should not become pregnant while on this medicationEffective birth control is necessary during treatment if your menopause status has not been confirmedYou should not breastfeed while receiving this medication.

Letrozole is a medication that is metabolized rapidly in the bodyIt is not thought to have significant levels in the blood or tissues for a prolonged period of time.

The most serious side effects seen with FEMARA are bone effectsfracturesdecreased bone density and osteoporosisand increases in cholesterolOther common side effects seen with FEMARA include joint painnauseaweight decreasevaginal irritationand pain in the extremitiesOther important less commonly reported side effects include blood clotsother cancersstrokeheart attack and endometrial cancer.

It is important to make sure you are taking the correct amount of medication every timeBefore every dosecheck that what you are taking matches what you have been prescribed.

You will take letrozole once a day by mouth and imatinib mesylate twice a day by mouth until intolerable side effects occur or until your tumor grows furtherYou will stop the treatment if your tumor grows or intolerable side effects occur.

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