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Patients should be monitored regularly for blood pressure determinations and serum electrolyte determinationssee WARNINGS

Infants born of mothers who have received substantial doses of fludrocortisone acetate during pregnancy should be carefully observed for signs of hypoadrenalism.

To avoid drug-induced adrenal insufficiencysupportive dosage may be required in times of stresssuch as traumasurgeryor severe illnessboth during treatment with fludrocortisone acetate and for a year afterwards.

In generaldose selection for an elderly patient should be cautioususually starting at the low end of the dosing rangereflecting the greater frequency of decreased hepaticrenalor cardiac functionand of concomitant disease or other drug therapy.

Prolonged use of corticosteroids may produce posterior subcapsular cataractsglaucoma with possible damage to the optic nervesand may enhance the establishment of secondary ocular infections due to fungi or viruses.

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