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Furthermore and in part, the lawsuit also claims that the aforementioned assertions are not only false, but that the company knew about the serious health complications from the use of plavix from its own studies and had been warned by the fda repeatedly to stop its fraudulent advertising.

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The number of patients experiencing the primary outcomeCV deathMIor strokewas 5829.3in the Plavix-treated group and 71911.4in the placebo-treated groupa 20relative risk reduction95CI of 1028p.

Chest pain due to heart problems poor circulation in their legsperipheral arterial diseasea heart attack a stroke.

As shown in Table 5 and Figure 4 and Figure 5 belowPlavix significantly reduced the relative risk of death from any cause by 7p=0.029and the relative risk of the combination of re-infarctionstroke or death by 9p=0.002

Table 3Active Metabolite Pharmacokinetics and Antiplatelet Responses by CYP2C19 Metabolizer Status.

Alternative300-600 mg PO oncethen 75 mg/day for 4 days before CAS in combination with aspirin 81-325 mg/day.

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